8/28/2023 0 Comments Int pneumatic compression deviceThe primary outcome of new proximal lower limb DVT did not differ significantly between the two groups (3.9% in the pneumatic compression group vs. The two groups were balanced at baseline: the mean age was 58 years, almost 80% of patients were medical admissions to the ICU, and two-thirds were receiving mechanical ventilation. Proximal venous ultrasonography of the lower limbs was performed 48 hours after randomization and then twice weekly if DVT was clinically suspected. In the control group, pneumatic compression was only permitted during times when pharmacologic thromboprophylaxis was interrupted. Although sequential compression devices with thigh-length sleeves were preferred, nonsequential devices and knee-length sleeves, as well as foot pumps, were permitted. In the pneumatic compression group, patients also received intermittent compression to both lower limbs for at least 18 hours per day. Both groups received pharmacologic thromboprophylaxis with unfractionated heparin or low-molecular-weight heparin. Adult patients expected to be in the intensive care unit (ICU) for at least 72 hours were randomized, using concealed allocation, to receive pneumatic compression (n = 991) or pharmacologic thromboprophylaxis alone (n = 1,012). In this international multicenter study, researchers investigated whether the addition of mechanical thromboprophylaxis with intermittent pneumatic compression would further reduce the risk of DVT in these patients. Current guidelines recommend pharmacologic thromboprophylaxis in all critically ill patients.
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